Epilepsy: Exploring INFORMATION / KNOWLEDGE / EMPOWERMENT MODULE 1: Epilepsy 101 4 What Are Seizures? Seizures are strong bursts of electrical activity in the neurons (nerve cells) of the brain.3,4 What Causes Seizures? During normal brain activity, nerve cells fire as different parts of the brain become activated. Different nerve cells alternate their firing patterns as they send their messages throughout the brain. During a seizure, large groups of nerve cells fire at the same time. A seizure is like an electrical storm in your brain.